Acid phosphatase activity, in the liver of larval and adult frogs following treatment with carbon tetrachloride, 1967

Davis, Ruthanne

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Title: Acid phosphatase activity, in the liver of larval and adult frogs following treatment with carbon tetrachloride, 1967
Author: Davis, Ruthanne
Date: 1967-08-01
Decade: 1960-1969
Abstract: The liver in both larval and adult frogs treated with carbon tetra-chloride was studied for general tissue damage and acid phosphatase activity. The animals sacrificed 2k hr after injection of carbon tetra-chloride and olive oil showed a marked acid phosphatase reaction. This enzymatic activity was localized in granular bodies predominantly along the bile canaliculi and also in the Kupffer cells. The control livers and those treated with olive oil only did not give a positive acid phosphatase reaction. The presence of a high acid phosphatase activity 2k hr after treatment with carbon tetrachloride suggested that tissues had been damaged. This observation was in keeping with the proposal that the hydrolytic enzymes contained within the lysosomal bodies of these cells had been released, in this instance by carbon tetrachloride poisoning.
Document Type: text
Format: application/pdf
Date of Award: 1967-08-01
Degree Type: thesis
Degree Name: Master of Science (MS)
Granting Institution: Atlanta University
Department: Department of Biology
Advisor: Hunter, Roy
Institution: Clark Atlanta University
Geographic Location: Georgia--Atlanta
Handle: http://hdl.handle.net/20.500.12322/cau.td:1967_davis_ruthanne
Rights Statement: http://rightsstatements.org/vocab/InC-EDU/1.0/